Friday, April 3, 2009

Xanax (Alprazolam)

Xanax concerns a subgroup triazolobenzodiazepines and enters into number 7 of the most popular preparations made in USA. Effects xanax have been in detail studied in laboratory of psychopharmacology of Institute of pharmacology. It is established that the given preparation possesses all basic displays of action which are peculiar benzodiazepines tranquillizers: anxiolytic, anticonvulsive, sedative, hypnotic, relaxante. However it possesses also a number of features which allocate it from the general group tranquillizers. The range of average doses xanax makes 0,25-4,5 mg/day, is thus observed accurate dosedependence effects. On anxiolytic it is essential activity Xanax, almost in 3 times, surpasses Valium, Rudotel, Buspirone. It does not concede In an average therapeutic dose (1 mg) powerful tranquillizers Rivotril and Ativan, but at application
of higher doses (to 5 and even 10 mg) have smaller activity, than these preparations.
The important feature anxiolytic effect Xanax is that it is not accompanied, as at others ataractics (Klonopin, Valium, Buspirone) sedative. The preparation has much bigger therapeutic width in comparison with others tranquillizers and большее stratification sedative, relaxante and anxiolytic action that defines its smaller side effects.
Alprazolam possesses moderated hypnotic effect, practically without breaking dream structure, causing only some reduction of 3 and 4 stages and a paradoxical phase of a dream. The basic hypnotic effect is expressed in period reduction dropping-off to sleep, increase in duration of a dream and decrease in quantity of night awakenings. Unlike traditional benzodiazepines, xanax possesses to straight lines independent antidepressant effect. Besides, it possesses expressed antistress and antipanic action. Primary mechanisms antidepressant effect a preparation remain incomprehensible, however is established that the preparation can exasperate noradrenergic transfer.
Essential interest is represented by experimental data that Xanax possesses positive cardioprotector action. The basic application in clinic Xanax has found in quality anxiolytic, antidepressant and antipanic means. It shows efficiency at neurosises, secondary neurotic frustration at somatic patients. At patients with functional and organic diseases of nervous system, a gastroenteric path and a skin, and also at abstinent syndrome at alcoholics.

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